Chromosome 2
Nemaline Myopathy

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Ehlers-Danlos Syndrome
Duane Retraction Syndrome
Nemaline Myopathy
CREB2
Calmodulin 2
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Inheritance of NM:

Nemaline myopathy is inherited by autosomal recessive.  That means both parents must be carriers of the disease, but don't have the disease.  There is a 25% chance that their child would have the disease.  There is a 50% of their child would be carriers of the disease (Myopathies 1).  

Symptoms of NM:

Having NM, would cause moderate weaknesses to voulnatry muscels.  Weakness in muscles of the arms, legs, and trunk.  Milld weakness of facial muscles.  Decreased or absent reflexes in affected muscles.   Long, narrow face, high-arched palate, and jaw projects beyond upper part of the face (Myopathies 1).   

Detection of NM:

Diagnosistic test can be tested to measure amount of potassium in blood.  Or test muscel biopsy.  Use electromyogram to test muscles tension (Myopathies 2).

Treatment for NM:

An infant with nemaline myopathy usually requires a feeding tube to deliver nutrition and mechanical ventilation to support respiration. Children and adults also can benefit from respiratory support, since respiratory failure during sleep can be a persistent danger. Mobility and strength can be improved significantly by physical and orthopedic therapies (Facts about diseases 2). 

Distal weakness
rodarm.jpg
http://www.neuro.wustl.edu/neuromuscular/syncm.html#rod